ADMIN/NON MEDICINE
STATISTICS
PromptLimitations of RCT’s
ResponseTranslation to different environments
Specific question studied may not be applicable to unique patient
Unique time peiord assessment bias
Bacground traits remain constant assumption
Averate treatment effects limitation
Specific question studied may not be applicable to unique patient
Unique time peiord assessment bias
Bacground traits remain constant assumption
Averate treatment effects limitation
PromptWhat is “Power” as it realates to a study
ResponseThe ability that the study will detect a predetermined differenc in measurement between 2 groups
‘Sensitivity’ of hypothesis testing
‘Sensitivity’ of hypothesis testing
PromptDeterminants useful in calculating sample size
ResponseEffect size
Degree of variation in the measured variable
Degree of certainty (significance)
Desired power of a study
Likely distribution of data
Degree of variation in the measured variable
Degree of certainty (significance)
Desired power of a study
Likely distribution of data
PromptDifferent measures of outcome a study can produce
ResponseNumbber needed to treat
Odds ratio
Relative risk reduction
Absolute risk reduction
Hazard ratio
Number needed to harm
Odds ratio
Relative risk reduction
Absolute risk reduction
Hazard ratio
Number needed to harm