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RESPIRATORY


EFUSION

Prompt
ResponseLarge pleural effusion + pneumothorax = hydropneumothorax
Tracheal deviation to left - radiologic signs of tension

No surgical emphysema
No oxygen tubing
No mass/infection seen
No bony lesions
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Prompt
ResponseHomogenous opacification right middle and lower zones
Loss of right hemidoaphragm
Rim of opacity around periphery of pleural cavity consistent with fluid

DDx
Parapneumonic effusion
Malignancy
PE
Hydrothorax from massive ascites
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Prompt30 M from Nepal with Fever
ResponseThere was no description of this. But you aspirate it.
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PromptUS RLL
ResponseEffusion
Loculated
Consolidated lung

Dx = Empyema
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PromptInvestigations in Pleural Effusion
ResponsePleural fluid culture - identify organisms and target antibiotic therapy
Pleural fluid biochemistry - LDH, Protein - Transudate vs exudate (lights criteria). Glucose, pH
Pleural fluid cytology - identify malignancy
Pleural fluid AFB ? TB
Serum protein + LDH for comparison (Light’s criteria)
CT - look for malignancy (Especially after fluid is drained)
CTPA - Diagnose PE
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PromptTransudate vs Exudate investigations
ResponseUse Lights criteria - you will need to order
Pleural fluid and serum LDH
Pleural fluid and serum Cholesterol
Pleural fluid and serum Albumin
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PromptWhat is lights criteria
ResponseExudate if 1 or more of
Pleural fluid protein:serum protein >0.5
Pleural fluid LDH:Serum LDH >0.6
Pleural fluid LDH > ⅔ upper value of serum LDH (Lab reference range

If equivocal
Serum albumin - pleural fluid albuman <1.2g/dL
Pleural fluid albumin >30g/L
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PromptCauses of pleural exudate
ResponseInfective - pneumonia, TB
Inflammatory - Rheumatoid arthritis, SLE, Dressler’s syndrome
Malignancy
PE (Pulmonary infarction from PE)
Benign asbestos related
Abdominal - pancreatitis, intraabdominal abscess, esophageal perforation, ascites
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PromptCauses of pleural transuadate
ResponseCCF
Cirrhosis

Hypoalbuminaemia
Hypothyroid
Nephrotic syndrome
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PromptIndications for thoracentesis of pleural effusion in ED
ResponseRespiratory compromise
Haemodynamic instability
Massive effusion with mediastinal shift
Some stable but symptomatic patients.
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PromptManagement of massive effusion
ResponseIdentify and establish goals of care
Improve oxygenation - O2 via NRBM
Decompression + Formal ICC insertion
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PromptPleural fluid findings suggestive of empyema
ResponsePurulent pleural fluid
Positive gram stain/culture
WCC >50,000
Pleural fluid glucose <3
Pleural fluid pH <7.2
Pleural fluid LDH >1000
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PromptManagement of Empyema
ResponseSupportive
  • Supplemental O2
  • Analgesia
  • Fluids/nutrition
Specific (medical)
  • IVABx - broad spectrum (Tazocin/cefepime, Add vancomycin if MRSA suspected)
  • Large bore chest drain ~20 F
Specific (Surgical)
  • Fibrinolytics via chest drain
  • VATS (Video assisted thoracoscopic surgery
  • Open thoracotomy
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PromptRisk factors for re-expansion pulmonary oedema after thoracocentesis
ResponseAge <30
Lung collapse >7 days
>3L pleural fluid
Use of suction
Rapid drainage >1.5L/hr
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