PAEDIATRICS
NEUROLOGY/SEIZURE
PromptExam findings prompting LP in febrile child
ResponseBulging fontanelle
Sick child - with some examination features to support this eg; Vital signs
Irritable/inconsolable
Apparent neck stiffness
No clear source of fever
Seizure but regained consciousness
Sick child - with some examination features to support this eg; Vital signs
Irritable/inconsolable
Apparent neck stiffness
No clear source of fever
Seizure but regained consciousness
PromptCauses of infant seizure
ResponseHYPOGLYCAEMIA
Febrile illness - CNS infection
Head trauma
Intracranial causes - Infection, structural abnormality, Bleed (NAI/Head injury)
Metabolic - hypoglycaemia, hyponatraemia, Inborn errors of metabolism
Genetic - infantile spasm
Cardiac - Long QT
Toxins
Febrile seizure
Hypoxia
Epilepsy
Infantile spasms
Go through THE MISFITS and start writing!
Febrile illness - CNS infection
Head trauma
Intracranial causes - Infection, structural abnormality, Bleed (NAI/Head injury)
Metabolic - hypoglycaemia, hyponatraemia, Inborn errors of metabolism
Genetic - infantile spasm
Cardiac - Long QT
Toxins
Febrile seizure
Hypoxia
Epilepsy
Infantile spasms
Go through THE MISFITS and start writing!
PromptInvestigations in paediatric seizure
ResponseBedside - Exclude metabolic, hypoglycaemia, toxin as cause
BSL
ABG/VBG
ECG
Lab
EUC, CMP, FBC - Exclude metabolic and infective causes
LP if no focal neurology or altered mental staus and suspect meningitis
Cultures
Neuroimaging
BSL
ABG/VBG
ECG
Lab
EUC, CMP, FBC - Exclude metabolic and infective causes
LP if no focal neurology or altered mental staus and suspect meningitis
Cultures
Neuroimaging
- MRI if focal neurology to suggest SOL or encephalitis
- CTB if traumatic brain injury
PromptManagment of infant seizure
ResponseSupport airway, High flow oxycent to maintain sats >92% (avoid hypoxia or hypercarpnoea)
Cessation of seizure
Cessation of seizure
- 1st line: midazolam IV 0.1-0.15mg/kg (Buccal or IN 0.3mg/kg) x 2 doses
- 2nd line: Levetiracitam 20-40 mg/kg or phenyton 20 mg/kg IV
- 3rd line Prepare for intubation (Thio/prop/ket or midaz)
- Pyridoxine 100m gIV in children under 6 months
- Correct hypoglycaemia 2 mL/kg 10% destrose
PromptFEBRILE CONVULSION
ResponseOSCE = talk to mum
PromptSimple febrile convulsion criteria
ResponseDiagnostic criteria: Fever and ALL of:
Age 6 months to 6 years
Simple less likely in developmental delay, progressive neurologic conditions, previous Afebrile seizures.
Look for signs of CNS infection
- Generalised tonic clonic seizure
- Duration <15 minutes
- Complete recovery within 1 hour
- Do not recur in the same febrile illness
Age 6 months to 6 years
Simple less likely in developmental delay, progressive neurologic conditions, previous Afebrile seizures.
Look for signs of CNS infection
PromptAfebrile febrile seizure
ResponseSeizures in an acute infecoius illness (particularly gastroenteritis) without documented fever
Features consistent with simple febrile seizure
Features consistent with simple febrile seizure
PromptComplex febrile seizure
ResponseFever and ANY of:
- Focal seizure at onset or during seizure
- Duration >15 mins
- Incomplete recovery within 1h
- Recurrence in same febrile illness
PromptInvestigations in febrile siezure
ResponseNo investigations are indicated in a simple febrile seizure, where the focus of infection can be identified clinically and the child returns to baseline mental state - (Probably should be immunised too)
Investigations for the source of fever, including lumbar puncture, should be guided by the nature of the presentation and age of the child. See fever
There is no role for EEG in simple febrile seizures and a limited role in complex febrile seizures
In a prolonged or focal febrile seizure, consider CNS imaging after consultation with a senior doctor
RCH
Answers basically justify an investigation to look for cause of fever
Easily justified:
Urine in girl <2yo - UTI common in girl <2
BSL - history of illness, poor intake, ? metabolic problems
Investigations for the source of fever, including lumbar puncture, should be guided by the nature of the presentation and age of the child. See fever
There is no role for EEG in simple febrile seizures and a limited role in complex febrile seizures
In a prolonged or focal febrile seizure, consider CNS imaging after consultation with a senior doctor
RCH
Answers basically justify an investigation to look for cause of fever
Easily justified:
Urine in girl <2yo - UTI common in girl <2
BSL - history of illness, poor intake, ? metabolic problems
PromptDischarge criteria in seizure
ResponseNormal obs, examination, tolerating fluid intake.
Source of fever identified and appropriate treatment/advise given
Clear follow up plan
Ability to access healthcare urgently in event of deterioration
Has safe means of getting home
Parental education/understanding of condition and long term implications
Parental plan for first aid in event of recurrence
Source of fever identified and appropriate treatment/advise given
Clear follow up plan
Ability to access healthcare urgently in event of deterioration
Has safe means of getting home
Parental education/understanding of condition and long term implications
Parental plan for first aid in event of recurrence
PromptRisk of epilepsy/repeat episodes
ResponseEpilepsy risk
No other risk factors ~1% (Similar to general population)
Fhx of neurodevelopmental problems, prolonged/focal, or febrile status increases risk
Recurrence
50% at 1 year old
30% 2 year old
No other risk factors ~1% (Similar to general population)
Fhx of neurodevelopmental problems, prolonged/focal, or febrile status increases risk
Recurrence
50% at 1 year old
30% 2 year old