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CARDIOLOGY


HOCM

Young patient collapse playing sport.
PromptHOCM history questions
ResponseExertional – presyncope or syncope
Lung symptoms – dyspnoea rest and exertional, PND, orthopnea. Etc
Palpitations - atrial and vent. Dysrhythmia
Chest pain - anginal
Family hx - cardiac sudden death/known HCM
(?prior Ix/Echo)
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PromptHOCM exam findings
ResponsePulse – sharp rising, jerky pulse
JVP – prominent a wave
Apex beat – double or triple
Auscultation – late systolic ejection murmur (left sternal edge), pansystolic murmur from MR (apex), 4th heart sound
Dynamic manoeuvres – murmur louder with Valsalva – softer with squatting (increases preload) & isometric exercise e.g. hand grip (increases afterload)
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PromptECG (Describe)
ResponseLeft ventricular hypertrophy with increased precordial voltages and non-specific ST & T abnormalities
Deep, narrow (“dagger-lioke”) Q waves in lateral +/- inferior leads
Left atrial enlargement - P mitrale
Signs of WPW – short PR, delta wave
Pre-cordial T inversion

Q waves – dagger Q’s V1-5 (with narrow complex QRS)
LVH by voltage
Diffuse ST/T changes with T wave inversion chest leads V2-5
Leftward axis 1 postive 2 equiphasic 3 negative
PR interval – ok if described short (borderline – 30% assoc. with WPW)
Interpretation – 1 mark = Highly suspicious for HCM (or HOCM)

Non-specific global ST-segment depression (?c/w LVH/LMCA but age 15)
iii. aVR, V1, V2 ST segment elevation (?c/w LMCA but age 15)
iv. P-wave abnormalities (large P-waves globally/retrograde P-wave V2)
v. PR interval normal (i.e. no short PR)
vi. Sinus rhythm (i.e. no arrhythmia)
vii. Non-specific T-wave changes especially laterally (?c/w LVH)
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PromptECG (interpret)
Response
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PromptInitial investigations in suspected HOCM
ResponseBedside serial ECG for dynamic changes
Bloods troponin - ischaemia (+/_ serial)
CXR cardiomegaly, pulmonary congestion
Cardiac Echo ?hypertrophy ?dynamic outflow obstruction, wall motion abnormality etc
Can have one of fbc.tft.bsl (something sensible) – alternative dx for symptoms
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PromptList causes of anterior TWI
ResponseArrythmogenic RV Dysplasia
Myocardial ischaemia
Myo/pericarditis
PE
SAH
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Prompt(incidentally seems to be a big theme dx of HOCM then the 16 yo DAMA’s)
ResponseCounsel patient as to ddx and possible severity/ramification e.g. sudden death
Mother/responsible guardian involvement as technically minor under 18 (but could give valid consent to treatment being over 16)
?capacity assessment - retain, understand etc.
(Other colleague involvement early e.g. expedite cardio r/v/Echo if able)
Documentation
Something sensible!
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PromptList the most important complications of HOCM
Responsei. Ventricular arrhythmia

ii. Sudden death

iii. Risk to offspring (genetic transmission)

iv. Abnormal coronary arteries (ischaemia risk increased)
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PromptList management priorities during admission for initial diagnosis of HOCM
Responsei. Telemetry/monitoring for arrhythmia*
ii. Exclusion of valvular pathology/LVOT(echo)*
iii. Parental counseling
iv. Patient counseling re sport/activity
v. Beta-blocker
vi. Consideration for electrophysiological studies
vii. Consideration for implantable defibrillator
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